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Glycerine vs. Bisacodyl 2/18/2009

Why isn't glycerine used instead of bisacodyl in nursing homes for bowel protocol? Isn't long term use of stimulant harmful to bowel function?

Glycerine or glycerol is seldom given orally. When used as a rectal suppository it acts as a hyperosmotic laxative. We think of it as a lubricant because it acts like a soap and pulls water into the rectum. It is a stimulant and irritant just like bisacodyl but with action only at the rectosigmoid.

Eric G. Tangalos, MD, FACP, AGSF, CMD
Professor of Medicine
Mayo Clinic College of Medicine
Rochester, MN

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