Advances in Severe Asthma Management
A 2-Part Series
While poor asthma control is frequently attributed to poor adherence to prescribed medications and/or recommended environmental restrictions, 5% to 10% of patients experience poor control because they suffer from an underlying severe asthma pathophysiology characterized by airway inflammation resistant to conventional therapy. Severe asthma is a heterogeneous condition that consists of multiple phenotypes. It is now possible to identify different phenotypes as defined by characteristic clinical symptoms, pathophysiological mechanisms, and biomarkers. These activities will examine the pathophysiology of severe asthma, as well as treatments tailored to various phenotypes.
Nicola A. Hanania, MD, MS