CME Corner

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Program Detail

Release Date: September-15-08
Credit Expiration Date: September-30-09


Paul M. Ridker, MD, MPH
Eugene Braunwald Professor of Medicine
Harvard Medical School
Director, Center for Cardiovascular Disease Prevention
Brigham and Women’s Hospital
Boston, Massachusetts

Harry L. Leider, MD, MBA
Senior Fellow, Department of Health Policy & Outcomes
Thomas Jefferson University
Philadelphia, Pennsylvania

Credit Hours

Physician CME: 1.0
Pharmacist CPE: 1.0 (0.10 CEUs)


Online Presentation

Program Description


This is the first program in a 2-part series.

Using published guidelines to identify patients at risk for primary or secondary cardiovascular events is a practice that has withstood the test of time and has saved many lives. However, the science of atherosclerosis and the understanding of who is at risk for atherothrombosis has evolved, forcing clinicians to look beyond traditional risk factors. While cholesterol, specifically low-density lipoprotein (LDL) has been proven to be causative of atherosclerosis, the role of inflammation is revealing itself to be just as important to the pathophysiology of this disease. The effect that lipoproteins and inflammatory mediators have on endothelial function is still being explored, even as the costs and consequences of arterial plaque buildup are being continuously realized. This online capture of a live audioconference examines the science of atherosclerotic disease development, exploring the role of lipids, inflammation, and endothelial dysfunction in its pathogenesis. The cost effective benefits of both primary and secondary prevention of atherosclerotic disease endpoints are carefully examined in this first of a two-part series.

Program Developer/Facilitator


Target Audience

Managed care medical directors, pharmacy directors, and other physicians and pharmacists interested in the management of atherosclerosis.

Learning Objectives

Upon completion of this educational activity, the participant should be able to:

  1. Explain recent developments in the evolving concept of the biology of atherosclerosis and atherothrombosis.
  2. Review the health care burden of atherosclerosis and the financial value to payors that could be realized by focusing on primary as well as secondary prevention.
  3. Evaluate available diagnostic tests used to assess inflammation and atherosclerosis.


It is the policy of NAMCP and ProCE to ensure independence, objectivity, scientific rigor, and integrity in all of its continuing education activities. The faculty must disclose to participants any significant relationships with commercial interests whose products or devices may be mentioned in the activity or with the commercial supporter of this continuing education activity. Identified conflict of interest is resolved by NAMCP prior to accreditation of the activity.

Dr. Ridker has received funding for clinical research from AstraZeneca, Merck, Novartis, and sanofi-aventis. He has also served as a consultant to AstraZeneca, Dade-Behring, Merck-Schering Plough, and Novartis. He is also listed as a co-inventor on patents held by the Brigham and Women's Hospital that relate to the use of inflammatory biomarkers in cardiovascular disease.

Dr. Leider has no current financial relationships that present a conflict of interest. Formerly of XLHealth Inc., Dr. Leider will be providing examples and methodology collected by XLHealth Inc. within his presentation. XLHealth Inc. offers Medicare Health Plans and provides disease management and wellness support services to chronically ill patients and their physicians, as well as to health plan providers and government entities.

Credit Statements

Physicians: This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the National Association of Managed Care Physicians (NAMCP) and Medical Communications Media, Incorporated. NAMCP is accredited by the ACCME to provide continuing medical education for physicians.

NAMCP designates this educational activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Pharmacists: ProCE, Inc. is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. ACPE Universal Program Number 221-999-08-099-H01-P has been assigned to this home study program (initial release date 09-15-08). This program is approved for 1.0 contact hours (0.10 CEUs) in states that recognize ACPE providers. The program is provided at no cost to participants. Statements of credit will be issued online upon completion of the program evaluation and the post-test with a score of 70% or higher. No partial credit will be given.

Commercial Support Statements

This activity is supported by an educational grant from AstraZeneca.


  1. Please turn off all pop-up blockers.
  2. Click on the “start program” icon. This will bring you to the login/registration page where you will be able to register as a new member or update/correct existing registration information. When ready, click on the “continue to program” icon at the bottom of the screen. This will take you to a brief pre-program survey.
  3. The next screen will permit you to check for or download the Flash player required to run this program.
  4. Clicking “start the program” will allow you to begin the program presentation. This activity will require approximately 60 minutes to complete.
  5. Upon completion of the program, click on the post-test button to access the post-test and program evaluation. This will bring you to a brief post-program survey.
  6. Instructions for completing and submitting the post-test are provided on the post-test screen. A minimum score of 70% on the post-test is required for a CME/CPE statement of credit. Two attempts are allowed.

Certificate Fee



©2008, Medical Communications Media, Inc. All rights reserved. None of the contents may be reproduced in any form without prior written permission of the publisher. The opinions expressed in this program are those of the speakers and do not necessarily reflect the opinions or recommendations of their affiliated institutions, the publisher, the National Association of Managed Care Physicians, ProCE, or AstraZeneca. Any medications or other diagnostic or treatment procedures discussed by the program speakers should not be utilized by clinicians without evaluation of their patients’ conditions and of possible contraindications or risks, and without a review of any applicable manufacturer’s product information and comparison with the recommendations of other authorities.

By clicking START PROGRAM I acknowledge that I have read the CME/CE information above.

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